While for most children, COVID-19 is a mild illness, providers should be aware of the rare but serious Multisystem Inflammatory Syndrome in Children (MIS-C). Children with this condition present with symptoms of systemic inflammation, and can have clinical similarities to Kawasaki Disease, toxic shock syndrome and macrophage activation syndrome. Prominent features include fever, abdominal pain, cardiac involvement and rash, among others.
Children with possible Multisystem Inflammatory Syndrome in Children (MIS-C) require evaluation by a pediatric specialty team experienced in the diagnosis of Kawasaki Disease and other inflammatory conditions of childhood. If you have a possible case of MIS-C, page the infectious diseases physician on call at BC Children’s Hospital for further discussion and triaging. If cardiac imaging is needed, please liaise with the pediatric cardiologist BC Children’s Hospital. Both specialists can be reached through central paging at 1-604-875-2000. Further information is available in Multisystem Inflammatory Syndrome in Children (MIS-C) Temporally Associated with COVID-19: Guidance for Clinicians in B.C
Cases of MIS-C are reportable under the Reporting Information Affecting Public Health Regulation and Public Health Act. Please contact your local Medical Health Officer to report cases of MIS-C.