LGV can cause open sores in the genital area, swelling of the lymph nodes in the groin accompanied by fever and fatigue. Most recent cases have presented with proctitis (inflammation of the rectal walls), often with bloody discharge. Although affects to the groin lymph glands are different in both men and women, swelling of the genitals (elephantiasis) may occur in either sex. The later stage, more common in females, may cause swelling of the genitals and destruction of the genital tissues.
The time from infection to the development of the genital sore is 3 - 30 days. Proctitis symptoms or buboes (swelling of the lymph glands at the top of the legs) may occur 2 - 10 weeks from the time of infection.