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Rubella (German Measles)


Case definition

Confirmed case 

Laboratory confirmation of infection in the absence of recent (i.e., in the previous 28 days) immunization with rubella-containing vaccine:  

  • Isolation of rubella virus from an appropriate clinical specimen OR
  • Detection of rubella virus RNA OR
  • Significant (e.g. fourfold or greater) rise in serum rubella IgG antibody titre between acute and convalescent sera OR
  • Detection of rubella IgM antibody using a recommended assay in a person with an epidemiologic link to a laboratory-confirmed case or who had recently travelled to an area of known rubella activity 

Clinical illness in a person who is epidemiologically linked to a laboratory confirmed case  

Probable case

Clinical illness

  • In the absence of appropriate laboratory tests,       
  • In the absence of an epidemiologic link to a laboratory-confirmed case    
  • In a person who has recently travelled to an area of known rubella activity  

Definition of clinical illness

Clinical illness is characterized by fever and rash, and at least one of the following:

  • arthralgia/arthritis 
  • lymphadenopathy
  • conjunctivitis  
SOURCE: Rubella (German Measles) ( )
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