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Legionellosis

Case Definition

Confirmed Case

  • A confirmed case of legionellosis is defined as a clinical illness [1] with laboratory confirmation of infection:
    • isolation of Legionella sp. from respiratory secretions, lung tissue, pleural fluid, or other normally sterile fluids;
      OR
    • a significant (e.g. fourfold or greater) rise in Legionella sp. IgG titre between acute and convalescent sera;
      OR
    • seroconversion from non-reactive to IgG or IgM reactive or from IgM reactive to IgG reactive;
      OR
    • demonstration of L. pneumophila antigen in urine;
      OR
    • demonstration of Legionella spp. DNA by NAT from respiratory secretions, lung tissue, pleural fluid, or other normally sterile fluids.

 

Notes

  1. Clinical illness is defined as two distinct illnesses: Legionnaires' disease, characterized by fever, myalgia, cough and pneumonia, and Pontiac fever, a milder illness without pneumonia. 

 

SOURCE: Legionellosis ( )
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