Laboratory confirmation of infection with/without symptoms from an appropriate clinical specimen (stool, intestinal fluid, or small bowel biopsy):
- demonstration of Cryptosporidium oocysts OR
- detection of Cryptosporidium DNA OR
- demonstration of Cryptosporidium antigen by an approved method (e.g. EIA, immunochromatographic – ICT)
Clinical illness in a person who is epidemiologically linked to a confirmed case
Clinical illness is characterized by diarrhea, abdominal cramps, loss of appetite, low-grade fever, nausea, and vomiting. The illness may be prolonged and life-threatening in severely immunocompromised persons.