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Our team is comprised of experts from every aspect of disease research. Together we seek answers to help ensure the health of all British Columbians as well as the wider world.

Faculty

Senior scientist, Environmental Health Services, BCCDC and Adjunct Professor University of British Columbia

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Dr. Reza Afshari (MD, MPH, and PhD in toxicology, and MSc certified in Epidemiology) is a toxicologist and epidemiologist, who focuses on environmental issues. He has published over 200 articles and 6 books. Chemical exposures (with a focus on trace elements), risk assessment, marine food safety and toxicity, drug use and overdoses have been his main field of research.


Dr. Afshari was awarded the "Young Affiliate of The World Academy of Sciences; –The 2007 TWAS young scientist - in biology/medicine". He was elected as the President of Asia Pacific Association of Medical Toxicology (APAMT) 2013-2014. He is currently acting as the Editor-in-Chief of the "Asia Pacific Journal of Medical Toxicology".


The most recent work from BCCDC projects and selected publications include:


Palad F, Bartlett K, Afshari R. Is Play-Dough a Vector for Transporting and Accumulating Lead? A Pilot Study Of Daycares in Greater Vancouver. Asia Pacific Journal of Medical Toxicology 2016 5(3), 72-74.


Randall A, Afshari R, Buxton J, Rate of peanut allergies amongst British Columbia residents from different countries of origin. (UBC MSc student project-2016-UBC - H16-00826)


Afshari R. Domoic Acid Exposure among the First Nation Population in BC. Marine Biotoxin Workshop - Oct 24-25, 2016. 


Afshari R. Domoic acid; epidemiology and toxicological regulation. UBC, School of Population and Public Health, University of British Columbia, Occupational and Environmental Health (OEH) Seminar Series, Friday January 29th 2016. http://spph.ubc.ca/seminar-series/oeh-seminars/


Afshari R, Golmohamadi K, Kosatsky T, et al. Further reduction of blood lead level via modification of Trail Area Health & Environment Program, Interior Health BC [in progress].


Taheri M, Mehrzad J, Afshari R, Saleh-Moghaddam M, Mahmudy Gharaie MH. Inorganic arsenic can be potent granulotoxin in mammalian neutrophils in vitro. J Immunotoxicol. 2016 Sep;13(5):686-93. 

Head of the Vaccine Research Laboratory, BC Centre for Disease Control Professor, Department of Medicine, University of British Columbia


 


Dr. Robert C. Brunham is the Head of the Vaccine Research Laboratory at the BC Centre for Disease Control (BCCDC). Until 2014, he was also the Executive and Scientific Director of the BCCDC. Dr. Brunham is also a Professor of Medicine at The University of British Columbia. He has over 350 publications and an h-index of 55, as calculated by ISI’s Web of Knowledge. He is internationally regarded as an expert on infectious diseases and widely known for his research on Chlamydia, SARS and HIV.


In 2005 Dr. Brunham received the CIHR Partnership Award for exemplifying research excellence by bringing health research communities together. His belief in seeking fundamental understanding of scientific problems while maximizing their benefit to society has been characterized by a career of partnership across the broad breadth of medical biosciences including molecular biology, clinical investigation and public health studies.


In Chlamydia research, Dr. Brunham is a world authority. He has made seminal contributions to defining the clinical features of infection in women, evaluating the impact of screening and treatment control programs, determining the underlying mechanisms of immunity, and discovering protective antigens suitable for vaccine development. He has innovatively analyzed the impact of public health efforts to control Chlamydia, deduced that the strategy is arresting the development of immunity and developed the rationale that a vaccine will be essential to Chlamydia control.


Dr. Brunham is well known for his work in elucidating the SARS genome, defining the characteristic clinical features of SARS infection and tracing its distinctive epidemiology to underlying network transmission dynamics. Using team science, he collaborated in accelerating the successful development of a vaccine for SARS.


Dr. Brunham’s contribution to understanding HIV is significant. He collaborated in determining the major role of chancroid in concentrating accelerated HIV transmission among high-risk groups in Africa and the major role of HLA molecules in HIV resistance and susceptibility.


For more information about Dr. Brunham's Chlamydia research, please click here.


To contact Dr. Brunham, please email him at robert.brunham@bccdc.ca


Collingro A, Tischler P, Weinmaier T, Penz T, Heinz E, Brunham RC, Read TD, Bavoil PM, Sachse K, Kahane S, Friedman MG, Rattei T, Myers GS, Horn M. Unity in variety--the pan-genome of the chlamydiae. Mol Biol Evol. 2011 Dec;28(12):3253-70.


Zoraghi R, Warroll L, See RH, Strangman W, Popplewell WL, Gong H, Samaai T, Swayze RD, Kaur S, Vuckovic M, Finlay BB, Brunham RC, McMaster WR, Davies-Coleman MT, Strynadka NC, Andersen RJ, Reiner NE. MRSA pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities. J Biol Chem. 2011 Oct 26.


Zoraghi R, See RH, Axerio-Cilies P, Kumar NS, Gong H, Moreau A, Hsing M, Kaur S, Swayze RD, Worrall L, Amandoron E, Lian T, Jackson L, Jiang J, Thorson L, Labriere C, Foster L, Brunham RC, McMaster WR, Finlay BB, Strynadka NC, Cherkasov A, Young RN, Reiner NE. Antimicrob Agents Chemother. 2011 May;55(5):2042-53.


Cherkasov A, Hsing M, Zoraghi R, Foster LJ, See RH, Stoynov N, Jiang J, Kaur S, Lian T, Jackson L, Gong H, Swayze R, Amandoron E, Hormozdiari F, Dao P, Sahinalp C, Santos-Filho O, Axerio-Cilies P, Byler K, McMaster WR, Brunham RC, Finlay BB, Reiner NE. Mapping the protein interaction network in methicillin-resistant Staphylococcus aureus. J Proteome Res. 2011 Mar 4;10(3):1139-50.


D’Souza C, Kronstad J, Taylor G, Warren R, Yuen M, Hu G, Jung W, Sham A, Kidd S, Tangen K, Lee N, Zeilmaker T, Sawkins J, McVicker G, Shah S, Gnerre S, Griggs A, Zeng Q, Bartlett K, Li W, Wang X, Heitman J, Stajich J, Fraser J, Meyer W, Carter D, Schein J, Krzywinski M, Kwon-Chung K, Varma A, Wang J, Brunham R, Fyfe M, Ouellette B, Siddiqui A, Marra M, Jones S, Holt R, Birren B, Galagan J, Cuomo C. (in press) Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts. mBio. 2011 Feb 8;2(1):e00342-10.


Last Updated: March 5, 2015

 

Professor, School of Population & Public Health, UBC Epidemiologist and harm reduction lead BC Centre for Disease Control

MBBS (Medicine), MRCGP (General Practice UK), MHSc (Community Medicine), FRCPC (Community Medicine)

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Dr. Jane Buxton is a public health physician and professor at the University of British Columbia in the School of Population and Public Health. At the BC Centre for Disease Control she is a physician epidemiology with hepatitis and the medical lead for harm reduction.  She developed the inter-sectoral Drug Overdose and Alert Partnership (2011) and provincial Take-Home-Naloxone program (2012). She uses qualitative and quantitative approaches and includes people who use drugs in developing policy, program planning and evaluation and research.

For  her work regarding peer engagement: Click Here
For details about the take home naloxone program: Click Here
For more details her UBC profile:  Click Here
Her publications can be accessed at:  https://www.researchgate.net/profile/Jane_Buxton

Email: Jane.Buxton@bccdc.ca Tel: 604-707-2573


Last Updated: March 5, 2015

Medical Head, Provincial TB Services, BCCDC

TB Physician Consultant to the First Nations Health Authority and Yukon Government

Clinical Associate Professor, Faculty of Medicine, UBC



Dr. Victoria J Cook received her Bachelor's Degree from Brown University in Providence, Rhode Island. She obtained her Medical Degree and Internal Medicine training from the University of British Columbia, and completed a fellowship in Respirology at the University of Manitoba.  Dr. Cook is a Fellow of the Royal College of Physicians of Canada (Internal Medicine and Respirology).

 

Dr. Cook has been based at the BC Centre for Disease Control, Division of TB Control since 2002. As physician consultant for the on-reserve TB program (TBSAC), she became particularly interested in the implementation and evaluation of novel strategies to control tuberculosis (TB) in high-risk populations. Ongoing research includes exploring ways to improve LTBI diagnosis and treatment completion in persons at risk for TB.  Currently, she is now the Medical Head of Provincial TB Services.  She provides consultative services to the First Nations Health Authority and the Yukon Government.  She continues to provide clinical care in the Provincial TB Clinics and on the TB Ward at VGH.  She also supports TB programming across the province and nationally working with partners in the Regional Health Authorities and federal agencies. 

 

Dr. Cook is the co-chair of the BC TB Strategic Committee, working to implement the Provincial Strategic Plan for TB Prevention, Treatment and Control.  She is also the current President of the North American Region of The Union (International Union against TB and Lung Diseases).  Dr. Cook is a member of the Respiratory Division at Vancouver General Hospital, is a Clinical Associate Professor in the Faculty of Medicine at UBC, and is the current Training Program Director for UBC Adult Respirology.

 

Selected Publications:

 

Cost-effectiveness of post-landing latent tuberculosis infection control strategies in new migrants to Canada.  Campbell JR, Johnston JC, Sadatsafavi M, Cook VJ, Elwood RK, Marra F.  PLoS One. 2017 Oct 30;12(10):e0186778. doi: 10.1371/journal.pone.0186778. eCollection 2017.

 

Preventing Tuberculosis in a Low Incidence Setting: Evaluation of a Multi-lingual, Online, Educational Video on Latent Tuberculosis.  Gao J, Cook VJ, Mayhew M.

J Immigr Minor Health. 2017 Jun 5. doi: 10.1007/s10903-017-0601-9. [Epub ahead of print]

 

Impact of interferon-γ release assay on the latent tuberculosis cascade of care: a population-based study.  Roth DZ, Ronald LA, Ling D, Chiang LY, Cook VJ, Morshed MG, Johnston JC.  Eur Respir J. 2017 Mar 22;49(3). pii: 1601546. doi: 10.1183/13993003.01546-2016. Print 2017 Mar. No abstract available.

 

Tuberculosis and chronic kidney disease: an emerging global syndemic.  Romanowski K, Clark EG, Levin A, Cook VJ, Johnston JC.  Kidney Int. 2016 Jul;90(1):34-40. doi: 10.1016/j.kint.2016.01.034. Epub 2016 May 10. Review.

 

Knowledge and Perceptions of Latent Tuberculosis Infection among Chinese Immigrants in a Canadian Urban Centre.  Gao J, Berry NS, Taylor D, Venners SA, Cook VJ, Mayhew M.  Int J Family Med. 2015;2015:546042. doi: 10.1155/2015/546042. Epub 2015 Nov 24.

 

Whole-genome sequencing and social-network analysis of a tuberculosis outbreak. Gardy JL, Johnston JC, Ho Sui SJ, Cook VJ, Shah L, Brodkin E, Rempel S, Moore R, Zhao Y, Holt R, Varhol R, Birol I, Lem M, Sharma MK, Elwood K, Jones SJ, Brinkman FS, Brunham RC, Tang P. N Engl J Med. 2011 Feb 24;364(8):730-9. doi: 10.1056/NEJMoa1003176. Erratum in: N Engl J Med. 2011 Jun 2;364(22):2174.

 

Transmission network analysis in tuberculosis contact investigations. Cook VJ, Sun SJ, Tapia J, Muth SQ, Arguello DF, Lewis BL, Rothenberg RB, McElroy PD. J Infect Dis. 2007 Nov 15;196(10):1517-27. Epub 2007 Oct 31.

 


Last Updated: March 5, 2015

 

Physician Epidemiologist, CD Prevention and Control Services, BCCDC; Clinical Associate Professor, School of Population & Public Health, UBC


 

Dr. Eleni Galanis obtained her medical degree from the Universite de Sherbrooke in 1995 and a Master of Public Health from Harvard University in 1998. She trained in Family Medicine and Community Medicine at the University of Toronto as well as in the Field Epidemiology Training Program. She is a Fellow of the Royal College of Physicians of Canada. She has worked at Health Canada and with the World Health Organization Global Foodborne Infections Network. Dr. Galanis is currently working on provincial enteric and zoonotic disease surveillance, control and prevention at the BCCDC. She is also a clinical associate professor at the School of Population and Public Health at UBC. Her interests include the epidemiology of foodborne and waterborne infections and outbreak investigation and surveillance methods. Recent work includes the investigation of the study of chronic sequelae of enteric infections, the impact of climate change on waterborne disease and the integrated surveillance of pathogens along the foodchain.


Selected Publications:

Taylor M, Cox W, Otterstatter M, deWith N, Galanis E. Evaluation of agricultural interventions on human and poultry-related Salmonella Enteritidis in British Columbia. Food Path Dis. 2018;15(1):39-43.


Currie A, Galanis E, Chacon PA, Murray R, Wilcott L, Kirkby P, et al. Outbreak of E. coli O157:H7 infections linked to aged raw milk Gouda cheese, Canada, 2013. J Food Prot. 2018;81(2):325-331.


Chhetri BK, Takaro TK, Balshaw R, Otterstatter M, Mak S, Lem M, Zubel M, Lysyshyn M, Clarkson L, Edwards J, Fleury MD, Henderson SB, Galanis E. Associations between extreme precipitation and acute gastro-intestinal illness due to cryptosporidiosis and giardiasis in an urban Canadian drinking water system (1997-2009). J Water Health. 2017 Oct;15(6):898-907.


Konrad S, Paduraru P, Romero-Barrios P, Henderson SB, Galanis E. Remote sensing measurements of sea surface temperature as an indicator of Vibrio parahaemolyticus in oyster meat and human illness. Env Health. 2017;16:92.


Galanis E, Taylor M, Romanowski K, Bitzikos O, Jeyes J, Nowakowski C, Stone J, Paccagnella A, Forsting S, Li S, Hoang L. Evaluating the timeliness of enteric disease surveillance in British Columbia, Canada, 2012-13. Can J Infect Dis Med Microbio. 2017:1-8.


Acheson ES, Galanis E, Bartlett K, Mak S and Klinkenberg B. Searching for clues for eighteen years: Deciphering the ecological determinants of Cryptococcus gattii on Vancouver Island, British Columbia. Med Mycol. 2017;0:1-16.


Fong D, Otterstatter M, Taylor M, Galanis E. Analysis of enteric disease outbreak metrics, BCCDC, 2005-14. Can Comm Dis Rep. 2017;43(1):1-6.


Last Updated: March 5, 2015


 

Senior Scientist (Genomics & Molecular Epidemiology), BCCDC Communicable Disease Prevention and Control Services 

Assistant Professor, School of Population and Public Health, University of British Columbia 
Associate Member, Dept. of Microbiology & Immunology, University of British Columbia
Canada Research Chair in Public Health Genomics
Michael Smith Foundation for Health Research Scholar

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Dr. Gardy joined BCCDC in 2009, where she works in the emerging field of genomic epidemiology, combining whole genome sequencing with both new and old epidemiological techniques to understand the origins, evolution, and transmission dynamics of pathogens including tuberculosis, measles, and mumps. She is also a passionate science communicator involved in a number of science media projects, including regular appearances on CBC Television's documentary series The Nature of Things.

 

Dr. Gardy obtained her BSc in Cell Biology & Genetics from UBC in 2000 and completed her PhD at Simon Fraser University in 2006 under Dr. Fiona Brinkman, working on bacterial genomics and bioinformatics-based predictive methods. She then completed three years of postdoctoral training in the R.E.W. Hancock laboratory at UBC, using systems biology techniques to study the mammalian innate immune response and working on visualization tools to facilitate scientists' exploration of biological network data. 

Follow Dr. Gardy on Twitter: http://www.twitter.com/jennifergardy 

A full list of Dr. Gardy's publications is maintained at https://scholar.google.ca/citations?user=TJZBPkUAAAAJ


Selected recent work includes:

JL Gardy, NJ Loman. 2018. Towards a genomics-informed, real-time, global pathogen surveillance system. Nature Reviews Genetics.

A Crisan, G McKee, T Munzner, JL Gardy. 2018 Evidence-Based Design and Evaluation of a Whole Genome Sequencing Clinical Report for the Reference Microbiology Laboratory. PeerJ.

X Didelot, C Fraser, J Gardy, C Colijn. 2017. Genomic infectious disease epidemiology in partially sampled and ongoing outbreaks. Molecular Biology and Evolution.

JL Guthrie, JL Gardy. 2017. A brief primer on genomic epidemiology: lessons learned from Mycobacterium tuberculosis. Annals of the New York Academy of Sciences.

HA Hatherell, X Didelot, SL Pollock, P Tang, A Crisan, JC Johnston, Colijn C, Gardy JL. 2016. Declaring a tuberculosis outbreak over with genomic epidemiology. Microbial Genomics.


Last Updated: March 5, 2015

 

 

Medical Director, Clinical Prevention Services, BCCDC

Clinical Associate Professor, School of Population & Public Health, UBC


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Mark Gilbert received his medical degree from the University of Ottawa in 2000, a master's degree in health sciences and fellowship in community medicine from UBC in 2005. Dr. Gilbert has worked as field epidemiologist with the Public Health Agency of Canada, a Medical Health Officer in Vancouver Island Health Authority, and led provincial STI and HIV surveillance systems in both BC and Ontario. Currently, Mark is the Medical Director of Clinical Prevention Services at BCCDC, which is focused on the delivery of health promotion, harm reduction, prevention and treatment services related to tuberculosis, sexually transmitted infections, HIV, hepatitis B and C, mental health and substance use. Dr. Gilbert also leads the BC Online Sexual Health Services program which delivers innovative sexual health services through the internet, including a provincial sexual health education website (smartsexresource.com) and an internet-based testing program for HIV, STI and hepatitis C called (getcheckedonline.com).

 

Dr. Gilbert's research interests include implementation science, communicable disease epidemiology, gay men's sexual health, sexual health literacy, and digital public health.

 

Selected publications:

 

Gilbert M, Salway T, Haag D, Fairley CK, Wong J, Grennan T, Uddin Z, Buchner CS, Wong T, Krajden M, Tyndall M, Shoveller J, Ogilvie G. Use of GetCheckedOnline, a comprehensive web-based testing service for sexually transmitted and blood-borne infections in Vancouver, British Columbia. Journal of Medical Internet Research 2017; 19(3):e81.

 

Gilbert M, Taylor D, Michelow W, Grace D, Balshaw R, Kwag M, Lim E, Fischer B, Patrick D, Ogilvie G, Coombs D, Steinberg M, Rekart M. Sustained reduction in sexual behavior that may pose a risl of HIV transmission following diagnosis during early HIV infection among gay men in Vancouver, British Columbia. AIDS and Behavior, 2017 (Epub ahead of print).

 

Gilbert M, Haag D, Salway Hottes T, Bondyra M, Elliot E, Chabot C, Farrell J, Bonnell A, Kopp S, Andruschak J, Shoveller J, Ogilvie G. Get checked…where? The development of a comprehensive, integrated internet-based testing program for sexually transmitted and blood-borne infections in British Columbia, Canada. JMIR Research Protocols 2016;5(3):e186.

 

Gilbert M, Swenson L, Unger D, Scheim A, Grace D. Need for a robust and inclusive public health ethics review of the monitoring of HIV phylogenetic clusters for HIV prevention. Lancet HIV 2016; 3(10):e461.

 

Gilbert M, Cook D, Steinberg M, Kwag M, Robert W, Doupe G, Krajden M, Rekart M. Targeting screening and social marketing to increase detection of acute HIV infection in men who have sex with men in Vancouver, British Columbia.  AIDS, 2013; 27(16):2649-2654.

 


Last Updated: March 5, 2015

 

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Dr. Troy Grennan is currently the Physician Lead for the Provincial HIV/STI Program at the BC Centre for Disease Control, as well as a Clinical Assistant Professor in the Division of Infectious Diseases at the University of British Columbia.  He received his medical degree from McMaster University, followed by Internal Medicine training at the University of Toronto, and Infectious Diseases and Medical Microbiology training at McMaster University.  This was followed by a post-doctoral fellowship from the CIHR Canadian HIV Trials Network and a Masters in clinical epidemiology from the University of Toronto, where his research project focused on HPV in HIV-positive MSM.  Prior to his arrival in BC in January 2015, his work centered mainly around clinical HIV, STI and other infectious diseases, as well as anal cancer screening.  In addition to his role at the BCCDC, he also works in the anal cancer screening clinic at St. Paul's Hospital.  His research interests include HIV and STI prevention, HPV-associated disease and anal cancer, and MSM health, and he currently holds several grants in these areas.


Selected publications:

Deonarine A, Ogilvie G, Montgomery C, Makaroff S, Holgerson N, Grennan T, Gilbert M, Wong J. Trends in syphilis partner notification among gay, bisexual, and other men who have sex with men in British Columbia, 2010-2013.  Sex Transm Dis 2016; 43(8) 489-493.


Remis R, Liu J, Loutfy M, Tharao W, Rebbapragada A, Huibner S, Kesler M, Halpenny R, Grennan T, Brunetta J, Smith G, Reko T, Kaul R.  Prevalence of sexually transmitted viral and bacterial infections in HIV-positive and HIV-negative men who have sex with men in Toronto.  PLOS ONE 2016; 11(7):e0158090.


Wilton J, Kain T, Fowler S, Hart TA, Grennan T, Maxwell J, Tan DH.  Use of an HIV-risk screening tool to identify optimal candidates for PrEP scale-up among men who have sex with men in Toronto, Canada: disconnect between objective and subjective HIV risk.  J Int AIDS Soc 2016; 19(1):20777. doi: 10.7448/IAS.19.1.20777. eCollection 2016.


Gilbert M, Haag D, Grennan T.  Got checked where? Online STI testing now available in BC.  British Columbia Medical Journal 2016; 58 (2): 102-103.


Grennan T, Raboud J, Su D, and Loutfy M, and the CANOC Collaboration. HIV-infected individuals experiencing virologic blips ≥500 copies/mL HIV RNA are at higher risk for recurrent episodes of virologic rebound. The Journal of Infectious Diseases 2012; 205(8): 1230-1238.


Grennan T, Walmsley S.  Etravirine for HIV-1:  Addressing the limitations of the nonnucleoside reverse transcriptase inhibitor class.  Journal of the International Association of Physicians in AIDS Care 2009; 8(6): 354-363.

 

 

Senior Scientist, Environmental Health Services, BCCDC Assistant Professor, School of Population and Public Health, UBC


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As the Senior Environmental Health Scientist at the BCCDC, I lead a program of applied research and surveillance to support evidence-based policy for the province. This role requires me to be a generalist rather than a specialist, and my work spans a wide range of topics including: air pollution from all provincially relevant sources (wildfire smoke, residential woodsmoke, industry, road dust, shipping, and vehicles); extreme weather events; radon gas; food safety; water quality; and exposures managed by the Drug and Poison Information Centre (DPIC). Most of my work requires the collection, processing, integration, analysis, and visualization of large health and environmental datasets. My team works exclusively in R, and takes a leadership role in R training across the centre.


A full list of Dr. Henderson’s publications can be found here on Google Scholar.  Additionally, Dr. Henderson's Research Gate profile can be found here


Last Updated: March 5, 2015

 

Program Head, Public Health Advanced Bacteriology & Mycology, BC Public Health Microbiology & Reference Laboratory, Provincial Health Services Authority Laboratories
Clinical Assistant Professor, Department of Pathology & Laboratory Medicine, UBC



Dr. Linda Hoang received her Master's and Medical Degrees from UBC and is FRCP(C) qualified in Medical Microbiology (UBC). She also obtained a Diploma in Tropical Medicine and Hygiene from the London School of Hygiene and Epidemiology, UK. Dr. Hoang has been formally based at the BC Centre for Disease Control as the Program Head for Bacteriology & Mycology laboratory since 2006, but has been involved in BCCDC-led projects in Vietnam and BC starting in 1998. She enjoys teaching and is the BCCDC site-supervisor for the UBC Medical Microbiology Residency Training Program. Her clinical and academic interests include agents of bioterrorism and containment level-3 pathogens, healthcare-acquired infections and antibiotic resistant organisms, Cryptococcus gattii, and enteric bacterial pathogens related outbreaks in BC.


Taylor M, Brisdon S, Jeyes J, Stone J, Embree G, Paccagnella A, Hoang L, Galanis E. Salmonella enterica serovar Agbeni, British Columbia, Canada, 2011. Emerg Infect Dis. 2012 Sep;18(9):1542-3. 


Marra F, Patrick DM, Chong M, McKay R, Hoang L, Bowie WR. Population-based study of the increased incidence of skin and soft tissue infections and associated antimicrobial use. Antimicrob Agents Chemother. 2012 Dec;56(12):6243-9. 


Mataseje LF, Boyd DA, Hoang L, Imperial M, Lefebvre B, Miller M, Poutanen SM, Roscoe D, Willey BM, Mulvey MR. Carbapenem-hydrolyzing Oxacillinase-48 and Oxacillinase-181 in Canada, 2011. Emerg Infect Dis. 2013 Jan;19(1):157-60. 


Hottes TS, Lester RT, Hoang LM, McKay R, Imperial M, Gilbert M, Patrick D, Wong T, Martin I, Ogilvie G. Cephalosporin and Azithromycin susceptibility in Neisseria gonorrhoeae isolates by site of infection, British Columbia, 2006 to 2011. Sex Transm Dis. 2013 Jan;40(1):46-51.


 Al-Najjar A, Al-Rawahi GN, Hoang LM, Kollmann TR. Clostridium difficile Vertebral Osteomyelitis. Pediatr Infect Dis J. 2013 Apr 16. Epub ahead of print


Last Updated: March 5, 2015

 

Chief Bioinformatician, BC Public Health Microbiology & Reference Laboratory
Clinical Assistant Professor, Pathology & Laboratory Medicine, UBC


 


Dr. William Hsiao joined BCCDC Public Health Microbiology & Reference Laboratory in September 2011 as chief bioinformatician to lead the effort of applying microbial genomics and bioinformatics in public health diagnostic and reference laboratory. He completed his PhD at Simon Fraser University under Dr. Fiona Brinkman’s supervision and a post-doctoral fellowship in Dr. Claire Fraser’s laboratory at the Institute for Genome Sciences, University of Maryland School of Medicine. His current research focuses on developing bioinformatics applications and using next generation sequencing technologies to study microbial pathogens and microbial communities (microbiomes). He has participated in several genomics and metagenomics projects and is currently leading the effort to develop a bioinformatics platform to use whole genome sequencing to facilitate public health infectious disease outbreak investigations. This will be achieved by integrating data from genomic sequencing, clinical records, laboratory test results, and epidemiological investigations using semantic web technologies. Overall, his research aims to improve our understanding of the pathogens that make us sick and the microbiota that keep us healthy.


Selected publications: 


 Chu, Hsueh-Ting, William Hsiao, Jen-Chih Chen, Tze-Jung Yeh, Mong-Hsun Tsai, Han Lin, Wen-Wenn Liu, Sheng-An Lee, Chaur-Chin Chen, Theresa Tsao and Cheng-Yan Kao. "EBARDenovo: Highly accurate de novo assembly of RNA-Seq with efficient chimera-detection". Bioinformatics 29(8) (April 15, 2013).


Chu, Hsueh-Ting, William Hsiao, Theresa Tsao, Frank Hsu, Chaur-Chin Chen, Sheng-An Lee and Cheng-Yan Kao. "SeqEntropy: Genome-wide assessment of repeats for short read sequencing". PLoS One. 8.3 (March 27 2013).


Langille, Morgan, Matthew Laird, William Hsiao, Terry Chiu, Jonathan Eisen and Fiona Brinkman. "MicrobeDB: a locally maintainable database of microbial genomic sequences " Bioinformatics. 28.14 (2012): 1947 - 1948. 


 Hsiao, William, Liang Li, Zhenqiu Liu, Cheron Jones, Claire Fraser-Liggett and Ashraf Fouad. "Microbial transformation from normal oral microbiota to acute endodontic infections". BMC GENOMICS. 13.345 (July 28 2012).


Shulzhenko, Natalia, Andrey Morgun, William Hsiao, Michele Battle, Michael Yao, Oksana Gavrilova, Marlene Orandle, Lloyd Mayer, Andrew Macpherson, Kathy McCoy, Claire Fraser-Liggett and Polly Matzinger. "Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut". NATURE MEDICINE. 17.12 (November 20, 2011): 1585 - 1593. 


 Liu, Zhenqui, William Hsiao, Brandi Cantarel, Elliott Drabek and Claire Fraser-Liggett. "Sparse Distance Based Learning for Simultaneous Multiclass Classification and Feature Selection of Metagenomic Data". BIOINFORMATICS. 27.23 (December 1, 2011): 3242 - 3249. 


Thom, Kerri, William Hsiao, Anthony Harris, Colin Stine, David Rasko and Kristie Johnson. "Patients with Acinetobacter baumannii bloodstream infection are colonized in the gastrointestinal tract with identical strains". AMERICAN JOURNAL OF INFECTION CONTROL. 38.9 (November, 2010): 751 - 753.


Hsiao, William, Korine Ung, Dana Aeschliman, Jenny Bryan, Brett Finlay and Fiona Brinkman. "Evidence of a large novel gene pool associated with prokaryotic genomic islands". PLoS Genetics. 1.5:e62 (Nov 18 2005).


Last Updated: March 5, 2015

 

 

Senior Scientist Hepatitis Program, Clinical Prevention Services, BCCDC and Clinical Assistant Professor, School of Population & Public Health, UBC



Dr. Naveed Zafar Janjua is an epidemiologist and senior scientist with hepatitis program in the clinical prevention services at the BC Centre for Disease Control and Clinical Assistant Professor at School of Population and Public Health, University of British Columbia. Dr. Janjua is a Medical Doctor (MBBS) with a Masters of Science (MSc) degree in Epidemiology & Biostatistics and Doctorate in Public Health (DrPH). At BCCDC, his work involves surveillance, research and policy advice related to hepatitis. His research interest includes hepatitis B and C epidemiology, disparities in treatment access and disease outcomes, influenza epidemiology/immuno-epidemiology, and vaccine effectiveness. His global health research includes unsafe medical injections and transmission of blood borne pathogens, socio-economic disparities in health and nutritional transition in developing countries. Dr. Janjua also teaches a graduate course on epidemiologic methods at UBC School of Population and Public Health. 


Selected Publications: 

Yousafzai MT, Siddiqui AR, Janjua NZ. Health belief model to predict sharps injuries among health care workers at first level care facilities in rural Pakistan. Am J Ind Med. 2013 Apr;56(4):479-87. doi: 10.1002/ajim.22117. 


Skowronski DM, Janjua NZ, De Serres G, Purych D, Gilca V, Scheifele DW, Dionne M, Sabaiduc S, Gardy JL, Li G, Bastien N, Petric M, Boivin G, Li Y. Cross-reactive and vaccine-induced antibody to an emerging swine-origin variant of influenza A virus subtype H3N2 (H3N2v). J Infect Dis. 2012 Dec 15;206(12):1852-61. doi: 10.1093/infdis/jis500. 


Janjua NZ, Skowronski DM, De Serres G, Dickinson J, Crowcroft NS, Taylor M, Winter AL, Hottes TS, Fonseca K, Charest H, Drews SJ, Sabaiduc S, Bastien N, Li Y, Gardy JL, Petric M. Estimates of influenza vaccine effectiveness for 2007-2008 from Canada's sentinel surveillance system: cross-protection against major and minor variants. J Infect Dis. 2012 Jun 15;205(12):1858-68. doi: 10.1093/infdis/jis283.  

Janjua NZ, Skowronski DM, Hottes TS, Osei W, Adams E, Petric M, Lem M, Tang P, De Serres G, Patrick DM, Bowering D. Transmission dynamics and risk factors for pandemic H1N1-related illness: outbreak investigation in a rural community of British Columbia, Canada. Influenza Other Respi Viruses. 2012 May;6(3):e54-62. doi: 10.1111/j.1750-2659.2012.00344.x. 


Janjua NZ, Iqbal R, Mahmood B. Association of socioeconomic position with under- and over-nutrition in Pakistan. Ann Epidemiol. 2011 Dec;21(12):884-91. doi: 10.1016/j.annepidem.2011.08.006. 


Skowronski DM, Janjua NZ, De Serres G, Hottes TS, Dickinson JA, Crowcroft N, Kwindt TL, Tang P, Charest H, Fonseca K, Gubbay JB, Bastien N, Li Y, Petric M. Effectiveness of AS03 adjuvanted pandemic H1N1 vaccine: case-control evaluation based on sentinel surveillance system in Canada, autumn 2009. BMJ. 2011 Feb 3;342:c7297. doi: 10.1136/bmj.c7297. 


Janjua NZ, Hamza HB, Islam M, Tirmizi SF, Siddiqui A, Jafri W, Hamid S. Health care risk factors among women and personal behaviours among men explain the high prevalence of hepatitis C virus infection in Karachi, Pakistan. J Viral Hepat.2010 May;17(5):317-26. doi: 10.1111/j.1365-2893.2009.01230.x. 


For full list of publications and citations in Google Scholar click here.


For publications in PubMed click here.


Last Updated: March 5, 2015

 

 

Clinical Microbiologist & Program Head of Virology Lab, BCCDC Public Health Laboratory 
Clinical Assistant Professor, Department of Pathology and Laboratory Medicine, University of British Columbia


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Selected Publications: 

 

A.D. Olmstead, T.D. Lee, R. Chow, K. Gunadasa, B. Auk, M. Krajden, A.N. Jassem (2017). Development and validation of a real-time, reverse transcription PCR assay for rapid and low-cost genotyping of hepatitis C virus genotypes 1a, 1b, 2, and 3a. J Virol Methods. 244:17-22. 

 

D.M. Skowronski, C. Chambers, S. Sabaiduc, J.A. Dickinson, A.L. Winter, G. De Serres, S.J. Drews, A.N. Jassem, J.B. Gubbay, H. Charest, R. Balshaw, N. Bastien, Y. Li, M. Krajden (2017). Interim estimates of 2016/17 vaccine effectiveness against influenza A(H3N2), Canada, January 2017. Euro Surveill. 22(6). pii: 30460.

 

A.N. Jassem, F. Chou, Y. C. Yang, M.A.Croxen, K. Pintar, L. Hoang, N. Prystajecky (2016). Pooled nucleic acid amplification test for screening of stool specimens for shiga toxin-producing Escherichia coliJ Clin Micro. Accepted manuscript posted online 24 August 2016,doi:10.1128/JCM.01373-16.

 

A.N. Jassem, N. Prystajecky, F. Marra, P. Kibsey, K. Tan, P. Umlandt, L. Janz, S. Champagne, B. Gamage, G.R. Golding, M.R. Mulvey, B. Henry, L. Hoang (2016). Characterization of Clostridium difficile Strains in British Columbia, Canada: A Shift from NAP1 Majority (2008) to Novel Strain Types (2013) in One Region. Can J Infect Dis Med Microbiol. 2016:8207418. 

 

A.F. Lau, G.A. Fahle, M.A. Kemp, A.N. Jassem, J.P. Dekker, K.M. Frank (2015). Clinical Performance of Check-Direct CPE, a Multiplex PCR for Direct Detection of bla(KPC), bla(NDM) and/or bla(VIM), and bla(OXA)-48 from Perirectal Swabs.J Clin Microbiol. 53:3729-37. 

 


 

Associate Clinical Professor in the UBC Department of Medicine


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Dr. Jay Johnston is the Evaluation Lead at Provincial TB Services and a 2014 Michael Smith Foundation Scholar. He is Head of the Division of Respiratory Medicine at Vancouver General Hospital, Associate Clinical Professor in the UBC Department of Medicine and Associate Member of the UBC School of Population and Public Health. Dr. Johnston has a MPH from Harvard School of Public Health and a Grzybowski Fellowship in TB Research. His research interests include TB epidemiology, treatment outcomes, drug resistance and genomics.

 

Recent publications

The effect of text messaging on latent tuberculosis treatment adherence: a randomised controlled trial

JC Johnston, ML van der Kop, K Smillie, G Ogilvie, F Marra, ...

European Respiratory Journal 51 (2), 1701488

 

Treatment outcomes for isoniazid-resistant tuberculosis under program conditions in British Columbia, Canada

K Romanowski, LY Chiang, DZ Roth, M Krajden, P Tang, VJ Cook, ...

BMC infectious diseases 17 (1), 604

 

Cost-effectiveness of post-landing latent tuberculosis infection control strategies in new migrants to Canada

JR Campbell, JC Johnston, M Sadatsafavi, VJ Cook, RK Elwood, F Marra

PloS one 12 (10), e0186778

 

Molecular Epidemiology of Tuberculosis in British Columbia, Canada–A 10-Year Retrospective Study

JL Guthrie, C Kong, D Roth, D Jorgensen, M Rodrigues, L Hoang, P Tang, ...

Clinical Infectious Diseases

 

Effect of Intermittency on Treatment Outcomes in Pulmonary Tuberculosis: An Updated Systematic Review and Meta-analysis

JC Johnston, JR Campbell, D Menzies

Clinical Infectious Diseases 64 (9), 1211-1220

 

Impact of interferon-γ release assay on the latent tuberculosis cascade of care: a population-based study

DZ Roth, LA Ronald, D Ling, LY Chiang, VJ Cook, MG Morshed, ...

European Respiratory Journal 49 (3), 1601546


Last Updated: March 5, 2015

 

Medical Director, Environmental Health Services, BCCDC, Scientific Director, National Collaborating Centre for Environmental Health, and Clinical Professor, School of Population and Public Health, UBC 


Dr. Kosatsky is the Medical Director of Environmental Health Services at BCCDC and Clinical Professor at the UBC School of Population and Public Health. He obtained his BA and MD from the University of Manitoba (1971-75) and completed a Family Practice Residency at Memorial University (Newfoundland) and occupational medicine certification at the University of Dundee (Scotland). He was an Epidemic Intelligence Service Officer with the US Centers for Disease Control and Prevention and completed US Preventive Medicine Certification at the CDC and an MPH at Emory University. From 1986-2008, he was Associate Professor of Occupational Health and Epidemiology at McGill University, and a consultant physician and environmental health researcher with the Montreal Public Health Program. During 2004-5, he was epidemiologist with the WHO European Centre for Environment and Health in Rome, Italy, with responsibilities in the area of climate change and health. Dr. Kosatsky’s current research involves the health effects of air pollution and weather. As Scientific Director of the Public Health Agency of Canada-funded National Collaborating Centre for Environmental Health, he is active in capacity building and development of professional expertise across Canada in environmental health (see www.NCCEH.CA). He has particular expertise in the development of innovative environmental health surveillance tools. 


Selected Publications: 

Shum M, Perron S, Ayre R, Beaudet S, Comack E, Stuart T, Kosatsky T. Bed bugs and public health: New approaches for an old scourge. Can J Public Health 2012; 103(6):399-403. 


Durigon M, Kosatsky T. Calls managed by the BC Drug and Poison Information Centre following the 2011 nuclear reactor incident at Fukushima, Japan. Canadian Pharmacists’ J. 2012; 145 (6): 256-258. 


Edwards J, Henderson SB, Struck S, Kosatsky T. Characteristics of small residential and commercial water systems that influence their likelihood of being on drinking water advisories in rural British Columbia, Canada—a cross-sectional study using administrative data. J Water Health. 2012; 10(4):629-49.


Kosatsky T, Pollock SL, Henderson SB. Shifts in mortality during a hot weather event in Vancouver, Canada: rapid assessment with case-only analysis. Am J Public Health. 2012; 102(12):2367-71. 


Henderson SB, Kosatsky T. A data-driven approach to setting trigger temperatures for heat health emergencies. Can J Public Health. 2012; 103(3):227-30.


Last Updated: March 5, 2015

 

Medical Director of the BC Centre for Disease Control (BCCDC) Public Health Laboratory and Medical Head of Hepatitis, and Professor of Pathology and Laboratory Medicine at UBC


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I am currently the Medical Director of the BC Centre for Disease Control (BCCDC) Public Health Laboratory and Medical Head of Hepatitis. I am also a Professor of Pathology and Laboratory Medicine at the UBC. After earning my BSc and MD (1973-80) at McGill University I undertook Internal Medicine training at McGill University (1980-83). Thereafter I did a fellowship in Infectious Diseases at Stanford University (1983-86) and completed my Medical Microbiology residency at the University of Toronto (1986-87). Between 1991 and 1998, I was Section Head of Virology and Serology and an Infectious Diseases consultant at The Toronto Hospital (The University Health Network). In September 1998, I moved from Toronto to the BCCDC and the University of British Columbia. I am also an adjunct scientist with the Canadian Blood Services and member of the Canadian Blood Services Scientific and Research Advisory Committee.


My clinical research involves integration of hepatitis prevention and care services. My laboratory research involves in the application of molecular techniques to: diagnose viruses; assess correlates between infection and clinical disease; use molecular techniques to monitor antiviral efficacy; and track microbial infections for epidemiological purposes. I also have extensive clinical trials expertise and serve as a laboratory coordinator industry sponsored clinical trials.


I have been involved in various types of research domains including: hepatitis, influenza, human papillomavirus, HIV and molecular diagnostics and phylogenetics as well as the use of linked laboratory and administrative data to help understand how to measure population level health outcomes for policy making.


Below a selected list of recent publications:

1: Janjua NZ, Islam N, Kuo M, Yu A, Wong S, Butt ZA, Gilbert M, Buxton J, Chapinal N, Samji H, Chong M, Alvarez M, Wong J, Tyndall MW, Krajden M; BC Hepatitis Testers Cohort Team. Identifying injection drug use and estimating population size of people who inject drugs using healthcare administrative datasets. Int J Drug Policy. 2018 Feb 23;55:31-39.

 

2: Butt ZA, Shrestha N, Wong S, Kuo M, Gesink D, Gilbert M, Wong J, Yu A, Alvarez M, Samji H, Buxton JA, Johnston JC, Cook VJ, Roth D, Consolacion T, Murti M, Hottes TS, Ogilvie G, Balshaw R, Tyndall MW, Krajden M, Janjua NZ; BC Hepatitis Testers Cohort. A syndemic approach to assess the effect of substance use and social disparities on the evolution of HIV/HCV infections in British Columbia. PLoS One. 2017 Aug 22;12(8):e0183609.

 

3: Janjua NZ, Islam N, Wong J, Yoshida EM, Ramji A, Samji H, Butt ZA, Chong M, Cook D, Alvarez M, Darvishian M, Tyndall M, Krajden M. Shift in disparities in hepatitis C treatment from interferon to DAA era: A population-based cohort study. J Viral Hepat. 2017 Aug;24(8):624-630.

 

4: Cook DA, Smith LW, Law J, Mei W, van Niekerk DJ, Ceballos K, Gondara L, Franco EL, Coldman AJ, Ogilvie GS, Jang D, Chernesky M, Krajden M. Aptima HPV Assay versus Hybrid Capture(®) 2 HPV test for primary cervical cancer screening in the HPV FOCAL trial. J Clin Virol. 2017 Feb;87:23-29.

 

5: Janjua NZ, Chong M, Kuo M, Woods R, Wong J, Yoshida EM, Sherman M, Butt ZA, Samji H, Cook D, Yu A, Alvarez M, Tyndall M, Krajden M. Long-term effect of sustained virological response on hepatocellular carcinoma in patients with hepatitis C in Canada. J Hepatol. 2017 Mar;66(3):504-513.

 

6: Janjua NZ, Kuo M, Yu A, Alvarez M, Wong S, Cook D, Wong J, Grebely J, Butt ZA, Samji H, Ramji A, Tyndall M, Krajden M. The Population Level Cascade of Care for

Hepatitis C in British Columbia, Canada: The BC Hepatitis Testers Cohort (BC-HTC). EBioMedicine. 2016 Oct;12:189-195.

 

7: Montoya V, Olmstead A, Tang P, Cook D, Janjua N, Grebely J, Jacka B, Poon AF, Krajden M. Deep sequencing increases hepatitis C virus phylogenetic cluster detection compared to Sanger sequencing. Infect Genet Evol. 2016 Sep;43:329-37.

 

8: Cook DA, Mei W, Smith LW, van Niekerk DJ, Ceballos K, Franco EL, Coldman AJ, Ogilvie GS, Krajden M. Comparison of the Roche cobas® 4800 and Digene Hybrid Capture® 2 HPV tests for primary cervical cancer screening in the HPV FOCAL trial. BMC Cancer. 2015 Dec 16;15:968.

 

9: Olmstead AD, Joy JB, Montoya V, Luo I, Poon AF, Jacka B, Lamoury F, Applegate T, Montaner J, Khudyakov Y, Grebely J, Cook D, Harrigan PR, Krajden M. A molecular phylogenetics-based approach for identifying recent hepatitis C virus transmission events. Infect Genet Evol. 2015 Jul;33:101-9.

 

10: Montoya V, Olmstead AD, Janjua NZ, Tang P, Grebely J, Cook D, Richard Harrigan P, Krajden M. Differentiation of acute from chronic hepatitis C virus infection by nonstructural 5B deep sequencing: a population-level tool for incidence estimation. Hepatology. 2015 Jun;61(6):1842-50.

 


Last Updated: March 5, 2015

 

Dr. Marko Kryworuchko

Senior Scientist, BC Centre for Disease Control

Adjunct Professor, Chemical and Biological Engineering Department, UBC


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Dr. Kryworuchko is an Immunologist who joined the BCCDC and UBC in 2017. His research aims to better understand host-pathogen interactions at the cellular and molecular levels with the ultimate goal of developing new and more effective infectious disease therapeutics and vaccines. Recent efforts have been focussing on the cellular autophagy or "self-eating" pathway.  Autophagy, as its name suggests, allows the cell to engulf and degrade portions of its cytoplasm for use as an energy source, and to remove superfluous or defective organelles and proteins. However, the autophagy machinery of the cell is also critical for the elimination of certain intracellular pathogens such as Mycobacterium tuberculosis and HIV. Autophagy signals the presence of pathogen to the immune system, and mobilizes innate and adaptive immune cells including monocytes/macrophages, helper and killer T cells, as well as antibody-producing B lymphocytes. Projects at the BCCDC are evaluating autophagy-based therapeutics and vaccines against pathogens of major public health importance including Chlamydia, Salmonella, Carbapenem antibiotic resistant bacteria, and others.

 

Dr. Kryworuchko obtained his PhD in Microbiology and Immunology at the University of Ottawa. His thesis described molecular mechanisms regulating the expression and function of the cellular adhesion molecule CD44 in normal as well as Epstein-Barr Virus-infected and immortalized B lymphocytes. Subsequently, as a post-doctoral fellow at Institut Pasteur (Paris, France), he pursued interests in HIV immunopathogenesis, elucidating virus-induced defects in CD4 helper and CD8 cytotoxic T lymphocyte responses. Prior to joining the BCCDC, he has worked extensively in the areas of viral immunopathogenesis, programmed cell death, and vaccine R&D at the University of Saskatchewan, the University of Ottawa, and the Children's Hospital of Eastern Ontario.

 

For undergraduate and graduate student training opportunities in these exciting areas of research & development please inquire (Marko.Kryworuchko@bccdc.ca).


Program Head Zoonotic Diseases and Emerging Pathogens; Program Head, Parasitology- BCCDC Public Health Laboratory

Clinical Professor, Department of Pathology and Laboratory Medicine, UBC

 

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Dr. Muhammad Morshed, PhD, SCCM  is a public health clinical microbiologist at the British Columbia Centre for Disease Control's Public Health Laboratory in Vancouver, British Columbia, where he is the Program Head of the Zoonotic and Emerging Pathogens section.  Dr. Morshed initially came to the BCCDC in 1997 as the Head of Vector-borne disease and recently also took responsibility to manage the Parasitology area as well. He is also a Clinical Professor at the Department of Pathology and Laboratory Medicine, University of British Columbia.

 

Dr. Morshed received his PhD from the Yamaguchi University School of Medicine, Japan, in1994. He completed his specialty training at the Research Institute of Tuberculosis in Tokyo, Japan in 1996 and from the College of Natural Resources, University of California, and Berkeley in 1997. He also received SCCM certification from Canadian College of Microbiologists in 1998

 

In both his public health and his academic roles, besides providing advice to clinicians in his areas of expertise (emerging infections such as syphilis, Lyme disease and other zoonotic – diseases of animals that can infect humans), Dr. Morshed has also added significantly to the general knowledge and understanding of these diseases with more than 100-refereed scientific publications. In recognition of his work, he received 'Excellence in Clinical Services' award from the Department of Pathology and Laboratory Medicine in 2016 and a national 'Canadian Top 25 Immigration, people's choice award' in 2017.

 

Dr. Morshed actively is engaged in scholarly societies for many years. He served as an executive board member for the Canadian Association for Clinical Microbiology and Infectious Diseases (CACMID) from 2004-06. He has also served as a Treasurer for the Canadian College of Medical Microbiologists (CCM) since 2014.

 

Selected Publications:

 

Morshed MG, Singh AE.  2015. Recent trends in the serologic diagnosis of syphilis.

Clin Vaccine Immunol. 22(2):137-47

 

Morshed M, Li L, Lee MK, Fernando K, Lo T, Wong Q. 2017. Retrospective Cohort Study of Tick Paralysis in British Columbia. Vector Borne Zoonotic Dis. 17(12):821-824

 

Morshed M, Tang P, Petric M, Krajden M, Roth D, Henry B, Isaac-Renton J; BCCDC West Nile Virus Team. 2011. West Nile virus finally debuts in British Columbia 10 years after its introduction to North America.Vector Borne Zoonotic Dis.11(8):1221-4.

 

Mak S, Morshed M, Henry B. 2010. Ecological niche modeling of lyme disease in British Columbia, Canada. J Med Entomol. 47(1):99-105

 

Henry B, Crabtree A, Roth D, Blackman D, Morshed M. 2012 Lyme disease: knowledge, beliefs, and practices of physicians in a low-endemic area. Can Fam Physician. 58(5) e289-95

 

Clinical Microbiologist, Program Head, Zoonotic Diseases and Emerging Pathogens, BC Public Health Microbiology & Reference Laboratory, Provincial Health Services Authority Laboratories Clinical Professor, Department of Pathology & Laboratory Medicine, Faculty of Medicine, UBC

 


Dr. Morshed graduated from the University of Dhaka, Bangladesh and holds a PhD degree in Medical Microbiology from Yamaguchi University School of Medicine, Japan. He received his specialty training at the Research Institute of Tuberculosis in Tokyo, Japan and from the College of Natural Resources, University of California, Berkeley. Dr. Morshed holds memberships in the American Society for Microbiology, Canadian Association for Clinical Microbiology and Infectious Diseases, Japan Anti-Tuberculosis Association and is a registered member of the Canadian College of Microbiologists (CCM). He is also serving on the CCM Board of Directors. His laboratory is responsible for specialized serology testing, molecular testing and microbial fingerprinting, program evaluation and research. His research focuses on surveillance of zoonotic and emerging pathogens. Organisms of interest are Borrelia burgdorferi, Treponema pallidum, Cryptococcus gattii, Toxoplasma gondii, Helicobacter pylori and West Nile virus. His laboratory is also involved with field studies on zoonotic and vector-borne disease (mice, ticks and mosquitoes) across BC. Dr. Morshed is also recognized by the national and international research community for his expertise on Lyme disease and syphilis. He is also member of many provincial, national and international working groups and networks in the area of zoonotic and emerging pathogens. 


Selected publications: 

Somily AM, A Kambal, T Naeem, HA Babay, MA Hedaithy, AA Anazi, M Barry, AA Askah, M Morshed, T Murray. Brucella spp isolated from respiratory sample and grown in Mycobacterium growth indicator tube (MGIT). Ann Saudi Med. 2012 (Epub ahead of print) 


Smith B, Y Simpson, M Morshed, L Cowen, R Hof, C Wetherell, and C Cameron. Syphilis diagnosis - new proteins for a new perspective. 2012. J. Clin. Micro (accepted) 


Morshed M. Better syphilis infection detection in better patient care and disease prevention. BC Med. J. 2012. 54 (6): 306-307 


Henry, B, D Roth, R Reilly, L MacDougall, S Mak, M Li, and M Morshed. How big is the lyme problem? Using novel methods to estimate the true number of Lyme disease cases in British Columbia residents from 1997 to 2008. 2011. Vector-borne and Zoonotic Dieases. 2011. 11(7): 863- 868 


Norman, SAS. Raverty, E. Zabek S. Etheridge, JKB Ford L Hoang and M Morshed. Maternal-fetal transmission of Cryptococcus gattii in harbour porpoise EID. 2011.17(2):304-305

Last Updated: March 5, 2015

Medical Director, Immunization Programs & Vaccine Preventable Diseases, BCCDC, and Associate Professor, School of Population & Public Health, UBC

 


Monika Naus obtained her medical training at the University of Alberta and her training in community medicine at the University of Toronto. She then served as a federal field epidemiologist with the Laboratory Centre for Disease Control prior to starting her career in public health, with a focus on communicable disease prevention and control. Prior to joining the BCCDC in July 2001, she was the Provincial Epidemiologist in Ontario from 1997 to 2001, and Senior Medical Consultant in Vaccine Preventable Diseases and TB Control for the Ontario Ministry of Health from 1990 to 1997. She was a member of the Canadian National Advisory Committee on Immunization for 12 years, chairing it from 2003 to 2007, and overseeing the publication of the 2006 7th Edition of the Canadian Immunization Guide. She is a member of the national Advisory Committee and Causality Assessment which reviews serious adverse events following immunization received by the Canadian surveillance system. In BC she co-chaired the BC Immunization Subcommittee from 2005 through 2009 during its inaugural 4 years. She is a Fellow of the Royal College of Physicians of Canada and of the American College of Preventive Medicine. Her interests include various aspects of planning and evaluation of old and new immunization programs, surveillance of communicable diseases, and outbreak investigation. 


 More information about Dr. Naus can be found here.


 Selected Publications: 


Simon RM Dobson SRM, McNeil S, Dionne M, Dawar M, Ogilvie G, Krajden M, Sauvageau C , Scheifele DW, Kollmann TR, Halperin SA, Langley JM, Bettinger JA, Singer J, Money D, Miller D, Naus M, Marra F, Young E. Immunogenicity of 2 doses of human papillomavirus vaccine in younger adolescents versus 3 doses in young women. JAMA. 2013 ;309(17):1793-1802. doi:10.1001/jama.2013.1625.


Fisman DN, Chan CH, Lowcock E, Naus M, Lee V. Effectiveness and cost-effectiveness of pediatric rotavirus vaccination in British Columbia: a model-based evaluation. Vaccine. 2012 Dec 14;30(52):7601-7. doi: 10.1016/j.vaccine.2012.10.034. Epub 2012 Oct 26. 


Sahni V, Naus M, Hoang L, Tyrrell GJ, Martin I, Patrick DM. The epidemiology of invasive pneumococcal disease in British Columbia following implementation of an infant immunization program: increases in herd immunity and replacement disease. Can J Public Health. 2012 Jan-Feb;103(1):29-33. 


Scheifele DW, Naus M, Crowcroft NS, Dobson S, Halperin S, Bjornson G. Optimizing Canadian Public Immunization Programs: A Prescription for Action. Canadian Journal of Public Health. Accepted for publication in the May/June 2011 issue. 


Tan K, Anderson M, Krajden M, Petric M, Mak A, Naus M. Mumps Virus Detection During an Outbreak in a Highly Unvaccinated Population in British Columbia. Canadian Journal of Public Health. January/February 2011, Vol.102(1): 47-50. 


Kaboli F, Astrakianakis G, Li G, Guzman J, Donovan T, Naus M. Influenza Vaccination and Intention to Receive the Pandemic H1N1 Influenza Vaccine among Healthcare Workers of British Columbia, Canada: A Cross‐Sectional Study. Infection Control and Hospital Epidemiology October 2010, Vol. 31, No. 10: pp. 1017-1024. 


Last Updated: March 5, 2015

 

Professor, Faculty of Medicine, University of British Columbia Canada Research Chair, Global control of HPV related disease and cancer Senior Public Health Scientist, BC Centre for Disease Control Senior Research Advisor, BC Women's Hospital and Health Centre 


Dr. Gina Ogilvie is Medical Director of Clinical Prevention Services at the British Columbia Centre for Disease Control and an Associate Professor in the Departments of Family Practice, Obstetrics & Gynecology and the School of Population and Public Health. She obtained her medical degree and family practice certification at McMaster University, and then did a fellowship in Population Health at McMaster University. She completed her Masters of Science (MSc) in Clinical Epidemiology at the University of British Columbia, with a focus on the care of HIV positive women and her Doctor of Public Health (DrPH) at the University of North Carolina Gillings School of Global Public Health in HPV primary screening. Her clinical and research focus is on sexually transmitted infections, human papillomavirus, HIV in women and care for marginalized populations. She is co-principal investigator of the HPV FOCAL study, a large clinical trial in British Columbia examining new screening methods for cervical cancer.


Selected publications: 


 Ogilvie GS, Smith LW, van Niekerk DJ, Khurshed F, Krajden M, Saraiya M, Goel V, Rimer BK, Greene SB, Hobbs S, Coldman AJ, Franco EL. Women's intentions to receive cervical cancer screening with primary human papillomavirus testing. Int J Cancer. 2013;133(12):2934-43.


Ogilvie GS, Mitchell S, Sekikubo M, Biryabarema C, Byamugisha J, Jeronimo J, Miller D, Steinberg M, Money D M. Results of a community-based cervical cancer screening pilot project using human papillomavirus self-sampling in Kampala, Uganda. Int J Gynaecol Obstet 2013; 122 (2):118–123. 


Simon RM Dobson, Shelly McNeil, Marc Dionne, Meena Dawar, Gina Ogilvie, Mel Krajden, Chantal Sauvageau David W Scheifele, Tobias R Kollmann, Scott A Halperin, Joanne M Langley, Julie A Bettinger, Joel Singer, Deborah Money, Dianne Miller, Monika Naus, Fawziah Marra, Eric Young. A randomized controlled trial to assess immunogenicity of a two-dose quadrivalent human papillomavirus vaccine schedule in Canadian younger adolescents: Results to Month 36. Journal of the American Medical Association 2013; 309(17):1793-1802. 


Ogilvie GS, Krajden M, van Niekerk DJ, Martin RE, Ehlen TG, Ceballos K, Smith LW, Kan L, Cook DA, Peacock S, Stuart GC, Franco EL, Coldman AJ. Primary cervical cancer screening with HPV testing compared to liquid based cytology: Results of round 1 of a randomized controlled trial – the HPV FOCAL Study. British Journal of Cancer 2012 Dec 4;107(12):1917-24. 


Ogilvie GS, Anderson M, Marra F, McNeil S, Pielak K, Dawar M, McIvor M, Ehlen T, Dobson S, Money D, Patrick DM, Naus M. A Population-Based Evaluation of a Publicly Funded, School-based HPV Vaccine Program in British Columbia, Canada: Parental Factors Associated with HPV Vaccine Receipt. PLOS Medicine. 2010 May 4;7(5):e1000270.


Last Updated: March 5, 2015

 

Senior Scientist and Epidemiologist at BCCDC and Assistant Clinical Professor in the School of Population and Public Health, UBC.  

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Dr. Michael Otterstatter's work at BCCDC focuses on statistical and mathematical modeling of public health data in order to better understand disease epidemiology and to inform public health programs.  This work spans communicable and chronic diseases and recently includes modelling of HIV, tuberculosis and hepatitis C.  Much of Dr. Otterstatter's work involves collaboration and support to government and non-government stakeholders as a consultant and scientific advisor in epidemiology and biostatistics.  He currently co-teaches Surveillance and Monitoring in Public Health at UBC with Dr. Eleni Galanis and co-leads weekly statistical and computational workshops at BCCDC with Dr. Robert Balshaw.

Dr. Otterstatter holds a doctorate from the University of Toronto (2007), as well as MSc (2001) and BSc (1998) degrees from the University of Calgary.  Previously, he was a postdoctoral fellow with Health Canada (2007-2009) and worked in cancer surveillance with the Public Health Agency of Canada in Ottawa (2009-2012). 

 

Recent Selected Publications

Roth, D., Mak, S., Otterstatter, M.C., Wong, J., Cook, V., Johnston, J. Identification of spatial and cohort clusters of tuberculosis: An example using surveillance data from British Columbia, 1990-2013.  Social Science and Medicine, S0277-9536 (16): 30337-9. [Epub ahead of print]


Otterstatter, M.C., Amlani, A., Guan, H., Richardson, L., Buxton, J.A. Illicit drug overdose deaths resulting from income assistance payments: Analysis of the 'check effect' using daily mortality data.  International Journal of Drug Policy, 33: 83–87.

Crisan, A., Wong, H.Y., Johnston, J.C., Tang, P., Colijn, C., 

Otterstatter, M.C., Hiscoe, L., Parker, R., Pollock, S.L., Gardy, J.L. 2015. Spatio-temporal analysis of tuberculosis infection risk among clients of a homeless shelter during an outbreak. The International Journal of Tuberculosis and Lung Disease 19: 1033-1038.


De, P., Otterstatter, M.C., Semenciw, R., Ellison, L., Marrett, L., Dryer, D. 2014. Trends in incidence, mortality and survival for kidney cancer in Canada, 1986-2007.  Cancer Causes and Control 25: 1271-1281.


Galanis, E., Mak, S., Otterstatter, M.C., Taylor, M., Zubel, M., Kuo, M., Takaro, T., Michel, P. 2014. The association between campylobacteriosis, agriculture and drinking water: A case-case study in a region of British Columbia, Canada, 2005-2009.  Epidemiology and Infection 142: 2075-2084.


De, P., Dryer, D., Otterstatter, M.C., Semenciw, R. 2013. Canadian trends in liver cancer: A brief clinical and epidemiological overview. Current Oncology 20: e40–e43.


Otterstatter, M.C., Brierley, J.D., De, P., Ellison, L.F., MacIntyre, M., Marrett, L.D., Semenciw, R., Weir, H. 2012. Esophageal cancer in Canada: Trends according to morphology and anatomical location. Canadian Journal of Gastroenterology 26: 723-727.

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Medical Epidemiology Lead for Antimicrobial Resistance and the Do Bugs Need Drugs Project, BCCDC and Professor, School of Population & Public Health, UBC


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Dr. Patrick is an Infectious Diseases Specialist and Epidemiologist with a career interest in responding to emerging infectious diseases.

His current focus is on the broad effort to contain the threat of antimicrobial resistance in Canada and around the World. He is particularly interested in understanding the drivers of antibiotic utilization in the community and intervening to reduce unnecessary use.  


Follow his publications on pubmed: https://www.ncbi.nlm.nih.gov/pubmed/?term=patrick+dm

 

Last Updated: March 5, 2015

 

Dr. Natalie Prystajecky

Environmental Microbiologist, BCCDC Public Health Laboratory

Clinical Assistant Professor, Pathology and Laboratory Medicine, University of British Columbia.

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Dr. Natalie Prystajecky is an Environmental Microbiologist at the BCCDC Public Health Laboratory and a Clinical Assistant Professor in Pathology and Laboratory Medicine at the University of British Columbia. Her work is at the intersect of environmental exposures (food and water) and clinical outcomes. She uses emerging technologies to improve routine surveillance and outbreak investigations for foodborne and waterborne pathogens. she has received grant funding from the BCCDC Foundation, Canadian Water Network, NSERC, Genome BC and Genome Canada. Her current research interests include development of new water quality tests using metagenomics, targeted resequencing of wetland sediments to study the emergence of avian influenza strains and whole genome sequencing of Giardia and Salmonella. She is keen to promote the translation of research methods to routine testing in diagnostic and reference laboratories.

 

Selected Publications

 

Jassem A, Chou F, Yang C, Croxen M, Pintar KDM, Hoang L and Prystajecky N. 2016. Pooled nucleic acid amplification test for screening of stool Specimens for Shiga Toxin-producing Escherichia coli. Journal of Clinical Microbiology. DOI:10.1128/JCM.01373-16

 

Uyaguari-Diaz M, Chan M, Chaban BL, Croxen MA, Finke JF, Hill JE, Peabody MA, Van Rossum T, Suttle CA, Brinkman FSL, Isaac-Renton J, Prystajecky N and Tang P. 2016. A comprehensive metagenomics-based strategy to identify new markers of water quality in freshwater samples. Microbiome. 4:20 DOI: 10.1186/s40168-016-0166-1

 

Henrich N, Holmes N, Isaac-Renton J and Prystajecky N. 2016. Exploring readiness for new molecular water tests: Insights from interviews with policy makers, laboratory managers and watershed managers. Environment International. 89-90: 2-20.

 

Prystajecky N, Tsui CKM, Hsiao W, Ho J, Uyaguari-Diaz, Tang P and Isaac-Renton J. 2015. Molecular and whole genome characterization of Giardia waterborne isolates: mixes are common in surface water. Applied and Environmental Microbiology. 81(14): 4827-34.

 

Prystajecky N, FSL Brinkman, B Auk, JL Isaac-Renton, P Tang. 2014. Personalized genetic testing and norovirus susceptibility. 25(4): 222-224. Canadian Journal of Infectious Diseases and Medical Microbiology.

 

 
Physician Epidemiologist, BCCDC and Clinical Professor, School of Population & Public Health, UBC

Dr. Danuta Skowronski 

‎Dr. Danuta Skowronski is Epidemiology Lead responsible for surveillance, rapid response research and program/policy recommendations for Influenza and Emerging Respiratory Pathogens at the BC Centre for Disease Control (BCCDC). She has been recognized for her notable contributions around several major public health events such as SARS, avian influenza, the 2009 H1N1 pandemic, enterovirus D68 and for regular expert guidance around seasonal influenza—an annual re-emerging pathogen.

Dr. Skowronski is credited with having pioneered the test-negative design (TND), an epidemiological innovation for monitoring how well the annually reformulated influenza vaccine protects each year. The TND was recognized by Accreditation Canada in 2015 as an Innovative Leading Practice and has since revolutionized global capacity to monitor influenza vaccine benefits. Adopted by multiple countries worldwide, TND findings are now used twice each year by the World Health Organization to inform influenza vaccine strain selection in both hemispheres.

Dr. Skowronski has more than 130 publications, primarily related to influenza, and has participated in numerous provincial, national, and international expert advisory committees. She is regularly sought by the media for her thoughtful, calm and clear communication on influenza and other emerging pathogen issues.

Among her various recognitions and distinctions, Dr. Skowronski has received Awards of Excellence for contribution to Public Health from the BC Provincial Health Officer, and for contribution to Quality of Life from the BC Pharmacy Association. She was named Woman of Distinction in delivering the 15th Hycroft Lecture for the University of BC's Women's Club of Vancouver. In 2007, she was recipient of the University of BC President's Award for Public Education through Media and in 2010, the Vancouver SUN similarly recognized Dr. Skowronski, naming her among the 100 most influential women of BC. In 2011, she was awarded the James M. Robinson Award by the University of British Columbia, Faculty of Medicine for her significant contributions to public health and in 2015 her team was recognized for providing Excellence through Knowledge in receiving the Provincial Health Service Authority (PHSA) + Award. In 2016, the Georgia Straight featured Dr. Skowronski among five leading women making a difference in the health of Vancouver residents.

Dr. Skowronski completed her medical degree and family medicine training at Queen's University in Kingston, Ontario and completed a Master's of Health Sciences degree and a Fellowship in Community Medicine at the University of British Columbia. She is further certified with the American Board of Preventive Medicine and completed additional training with the London School of Hygiene and Tropical Medicine. She worked for several years as an associate Medical Health Officer in Surrey, BC gaining practical experience in public health before joining the BCCDC in 1998 to pursue her interests in surveillance, applied public health research and policy development.

Select publications: 

  1. De Serres G, Skowronski DM, Ward BJ, et al. Influenza vaccination of healthcare workers: critical analysis of the evidence for patient benefit underpinning policies of enforcement. PLoS One 2017; 12(1): e0163586. 
  2. Skowronski DM, Chambers C, Sabaiduc S, et al. A perfect storm: Impact of genomic variation and serial vaccination on low influenza vaccine effectiveness during the 2014-2015 season. Clinical Infectious Diseases 2016; 63: 21-32. 
  3. Skowronski DM, Chambers C, Gustafson R, et al. Avian influenza A(H7N9) infection in 2 travelers returning from China to Canada, January 2015. Emerging Infectious Diseases 2016; 22:71-4.
  4. Skowronski DM, Chambers C, Sabaiduc S, et al. Pre- and postpandemic estimates of 2009 pandemic influenza A(H1N1) seroprotection to inform surveillance-based incidence, by age, during the 2013-2014 epidemic in Canada. Journal of Infectious Diseases 2015; 211:109-14.
  5. Skowronski DM, Janjua NZ, De Serres G, et al. Low 2012-13 influenza vaccine effectiveness associated with mutation in the egg-adapted H3N2 vaccine strain, not antigenic drift in circulating viruses. PLoS One 2014;9:e92153.
  6. Skowronski DM, Hamelin ME, De Serres G, et al. Randomized controlled ferret study to assess the direct impact of 2008-09 trivalent inactivated influenza vaccine on A(H1N1)pdm09 disease risk. PLoS One. 2014;9:e86555. Doi: 10.1371/journal.pone.0086555.
  7. Skowronski DM, Janjua NZ, Tsafack EP, et al. The number needed to vaccinate to prevent infant pertussis hospitalization and death through parent cocoon immunization. Clinical Infectious Diseases 2012 2012; 54: 318-27.
  8. Skowronski DM, Janjua NZ, De Serres G, et al. Cross-reactive and vaccine-induced antibody to an emerging swine-origin variant of influenza A virus subtype H3N2 (H3N2v). Journal of Infectious Diseases 2012; 206: 1852-61. 
  9. Skowronski DM, Hottes TS, Chong M, et al. Randomized controlled trial of dose response to influenza vaccine in children aged 6 to 23 months. Pediatrics 2011; 128: e276-89. 
  10. Skowronski DM, De Serres G, Crowcroft NS, et al and the Canadian SAVOIR Team. Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during Spring-Summer 2009: four observational studies from Canada. PLoS Med. 2010 6;7(4):e1000258.

For full list of publications and citations in Google Scholar click here

For publications in PubMed click here.

Last Updated: January 4, 2017

 

Dr. Kate Smolina is the Director of the BC Observatory for Population and Public Health, a partnership between the Ministry of Health and all Health Authorities to advance non-communicable disease, injury, and risk and protective factor surveillance in BC.


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Prior to her current role, Kate worked as a Banting Postdoctoral Research Fellow at the University of British Columbia, looking at the full spectrum of factors that influence population medicine use and associated health outcomes.

Her interests include chronic disease surveillance, linked administrative data, and health policy. She holds a BSc in Bio-Medical Science from the University of Guelph and a PhD in Public Health from the University of Oxford.

Dr. Smolina's published research can be found here.


Adjunct Professor, School of Nursing, Faculty of Applied Science, University of British Columbia Senior Practice Leader, PHSA HIV Program, BC Centre for Disease Control


Meaghan Thumath, MSc, BSN, RN, is the senior clinical practice leader for the STOP HIV program at BCCDC. Her research interests include gender, health equity, Indigenous health, global health metrics, and HIV implementation science. A registered nurse by training, she has over 10 years of HIV experience in direct clinical care, teaching, and research. Meaghan completed a bachelor of science in nursing at the University of British Columbia and a masters of science in public health from the London School of Hygiene and Tropical Medicine. She is currently enrolled in a PhD on health equity and implementation science at the University of British Columbia. 


Meaghan also maintains an active clinical practice as an outreach nurse certified in advanced reproductive health and continues to provide HIV technical assistance to international organizations such as UNAIDS, the World Bank, and UNDP. As a senior leader with Vancouver Coastal Health, she was a clinical leader at Insite, North America's first supervised injection facility, and led the implementation of a treatment-as-prevention pilot that doubled the region's access to HIV testing and treatment. Meaghan has won multiple awards for her work in HIV across Canada, Africa, Eastern Europe, and Central Asia, including a Premier's Award for Innovation and an Excellence in Nursing Education Award from the College of Registered Nurses. 


Selected Publications: 

B. Ng, D. Moore, W. Michelow, R. Hogg, R. Gustafson , W. Robert, S. Kanters, M. Thumath , M. McGuire, M. Gilbert (2014). Relationship between disclosure of same sex sexual activity to providers and HIV diagnosis and other sexual health services for men who have sex with men : Canadian Journal of Public Health, 2014 Apr 16; 1 05(3): e186-91. 


J. Craig Phillips, Carrie De Palma, R. Paul Kerston , Todd Sakakibara, William Booth, Mary Petty, Linda Akagi, Meaghan Thumath (2012). Brief Report: Preliminary C ourse Impact Evaluation. University of British Colu mbia. 


Gustafson, R., Sandhu, J., MacDonald, L., Chu, T., Thumath, M., Heath, K., & Montaner, J. (2012). Popu lation-level monitoring of STOP HIV/AIDS pilot project activitie s across Vancouver, British Columbia. International Journal of Infectious Diseases, 16, e182. DOI:10.1016/j.ijid.2 012.05.740 


B. Lightfoot, C. Panessa, S. Hayden, M. Thumath, I. Goldstone, B. Pauly (2009). Gaining Insite: Harm Reduction in Nursing Practice. Canadian Nurse: Apr; 105(4):16-22. 


M Thumath, D Burrows, L Beletsky, et al. From Beyon d Boutique to Epidemic Control: Evaluation Report o f HIV prevention activities by International HIV/AIDS All iance Ukraine funded by the Global Fund to Fight AI DS, TB and Malaria (October 2009): AIDS Project Management Gro up, Sidney, Australia. 


Thumath, M, Nettleton C, Stephens C, Napolitano D ( 2009). Peoples of North America Section: Overview of the existing global knowledge on the social determinant s of Indigenous Health. WHO Commission on the Social Determinants of Health: World Health Organization.

Last Updated: June 17, 2015

Executive Medical Director, BC Centre for Disease Control Professor of Medicine, University of British Columbia



Dr. Mark Tyndall joined the BC Centre for Disease Control in September of 2014 as the Executive Medical Director. In addition, he was appointed as a deputy Provincial Health Officer, the Director of the UBC Centre for Disease Control Research Institute, and a Professor at the UBC School of Population and Public Health. Prior to coming to Vancouver, he was the Chief of the Division of Infectious Diseases at the University of Ottawa and a Senior Scientist at the Ottawa Hospital Research Institute. His career awards include the Michael Smith Foundation for Health Research Senior Scholar Award and the Ontario HIV Treatment Network Applied Research Chair. He is an author on over 200 peer-reviewed publications, with a focus on HIV care and prevention, drug use, and public health intervention research. 


Dr. Tyndall received his Medical degree and internal medicine training at McMaster University and his infectious diseases fellowship training at the University of Manitoba. He received a doctoral degree in epidemiology from Harvard University with a focus on health and human rights. He has conducted international research and consultation in a number of countries and resided in Kenya for 4 years as part of the WHO collaborative research group on HIV. From 1999 to 2010 he was the Program Director for Epidemiology at the BC Centre for Excellence in HIV/AIDS and was co-lead investigator on the evaluation of Insite, North America’s first supervised injection site. He has conducted numerous community-based research projects in Vancouver and Ottawa, including epidemiologic studies of HIV and Hepatitis C transmission, antiretroviral access among injection drug users, and health care utilization among marginalized populations. Dr. Tyndall is a strong advocate and leader for public health in Canada and has fostered a number of community-based collaborations that have led to health policy changes. He was the co-founder of Physicians for Refugee Health and has advocated for enhanced harm-reduction interventions and the de-criminalization of drug use. 


Recent Selected Publications


Lazarus L, Shaw A, LeBlanc S, Martin A, Marshall Z, Weersink K, Lin D, Mandryk K, Tyndall MW; PROUD Community Advisory Committee. Establishing a community-based participatory research partnership among people who use drugs in Ottawa: the PROUD cohort study. Harm Reduct J. 2014 Oct 13;11(1):26. 


Alavi M, Raffa JD, Deans GD, Lai C, Krajden M, Dore GJ, Tyndall MW, Grebely J. Continued low uptake of treatment for Hepatitis C virus in a large community-based cohort of inner city residents. Liver Int. 2014 Sep;34(8):1198-206. 


Klein MB, Rollet-Kurhajec KC, Moodie EE, Yaphe S, Tyndall M, Walmsley S, Gill J, Martel-Laferriere V, Cooper C; Canadian Co-infection Cohort Investigators Mortality in HIV-hepatitis C con-infected patients in Canada compared to the general Canadian population (2003-2013). AIDS. 2014 Aug 24;28(13):1957-65. 


Tu D, Belda P, Littlejohn D, Pedersen JS, Valle-Rivera J, Tyndall M. Adoption of the chronic care model to improve HIV care: in a marginalized, largely aboriginal population. Can Fam Physician. 2013 Jun;59(6):650-7. 


Deans GD, Raffa JD, Lai C, Fischer B, Krajden M, Amin J, Walter SR, Dore GJ, Grebely J, Tyndall MW. Mortality in a large community-based cohort of inner-city residents in Vancouver, Canada. CMAJ Open. 2013 May 23;1(2):E68-76.


Last Updated: March 5, 2015

 


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Dr. Jason Wong completed his medical school training at the University of Alberta and his post-graduate training in Family Medicine as well as Public Health and Preventive Medicine at the University of British Columbia.  He currently works as a Physician Epidemiologist in the Clinical Prevention Services division at the BC Centre for Disease Control where he leads the team for provincial surveillance of STI/HIV, Hepatitis C, and TB.  Dr. Wong is a Clinical Assistant Professor in the School of Population and Public Health.

 

Other researchers 

Dr Karuna Karunakaran’s present research at UBC CDC involves identifying vaccine targets for Chlamydia trachomatis. The overall objective of this project is to validate a novel dendritic cell-based immunoproteomics technology as a means of identifying novel T cell antigen candidates for the development of efficacious vaccines for important intracellular pathogens such as C. trachomatis. Dr Karunakaran’s past work at UBCCDC involved investigating the roles played by the C. pneumoniae bacteriophage phiCpn1 in relation to C. pneumoniae pathogenesis of atherosclerosis. His post-doctoral work with Dr. Julian Davies at the Department of Microbiology & Immunology at UBC involved studies on the mechanisms of antibiotic resistance in mycobacteria. In this work he studied the development of multiple antibiotic resistance in mycobacteria. His Ph.D. work in Molecular Microbiology involved characterization of temperature sensitive and copy number mutants of the broad-host-range plasmid RK2 in order to exploit its biology in different gram negative bacteria.

 

Research Manager, Hepatitis Services, BCCDC
Since receiving an MA in Anthropology from the University of Victoria, Liza has gained extensive experience in managing qualitative research projects on chronic illnesses including hepatitis C, diabetes, and HIV/AIDS. Liza manages multiple research projects for the Hepatitis Services Division including Enhanced Hepatitis Strain Surveillance research on acute hepatitis C and B. She is also a trainer for the QSR qualitative analysis software program, NVivo.


Stajduhar, K., Thorne, S., & McGuinness, L. (2010). Patient perceptions of helpful communication in the context of advanced cancer. Journal of Clinical Nursing.


 Butt, G. & McGuinness, L. (2008, August). Partnership working in health and social care (Better partnership working series). [Book Review]. International Journal of Integrated Care, 8, ISSN 1568-4156. Available from http://www.ijic.org/ 


 Butt, G., Paterson, B. L., & McGuinness , L. K. (2008). Living With the Stigma of Hepatitis C. Western Journal of Nursing Research, 30 (2), 204-221. 


 Paterson, B. L., Butt, G., McGuinness , L., & Moffat, B. (2006). The Construction of Hepatitis C as a Chronic Illness. Clinical Nursing Research, 15 (3), 209-224. 


Thorne, S., Con, A., McGuinness , L., McPherson, G., & Harris, S. R. (2004). Health Care Communication Issues in Multiple Sclerosis: An Interpretive Description. Qualitative Health Research, 14 (1), 5.

 

Dr Hong Yu graduated with a PhD in Immunology from Shanghai Medical University, China in 2001. Dr Yu undertook post-doctoral training for five years at the Vaccine and Infectious Disease Organization (VIDO), University of Saskatchewan, where her research involved the development of methodologies for vaccination against hepatitis C using DNA/protein or dendritic cell-based vaccination regime. Dr Yu joined The Brunham Vaccine Laboratory as a research associate in 2007. Her present research interest focuses on Chlamydia vaccine discovery by identifying T cell antigens and exploring innovative adjuvants to develop a subunit vaccine against Chlamydia infection. 

 

 
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