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William Hsiao

William Hsiao is Chief Bioinformatician in the BC Public Health Microbiology & Reference Laboratory at BCCDC. He is also a clinical assistant professor in Pathology & Laboratory Medicine at UBC.


Dr. Hsiao directs the Public Health Bioinformatics Group at BCCDC PHL, an interdisciplinary group of researchers interested in solving practical public health problems through research and transforming public health practice using innovative technologies. Our research combines knowledge engineering techniques and bioinformatics tools to improve data sharing and integrated analysis in public health. 

We study microbes in isolation (genomics) and in communities (metagenomics) using high-throughput sequencing and other *omics techniques. This leads to better disease diagnostics and intervention so public health practitioners can response to outbreaks more rapidly and effectively. Recognizing the One Health nature of many infectious diseases, we collaborate extensively with researchers and practitioners from a wide range of disciplines in quantitative sciences, social sciences and biological sciences. Overall, our research program aims to improve understanding of the pathogens that make us sick and the microbiota that keep us healthy.


Dr. Hsiao joined BCCDC Public Health Laboratory in September 2011 as chief bioinformatician and subsequently became a senior scientist (bioinformatics) in January 2017. He is dedicated to bioinformatics education and outreach - serving as an instructor for the Canadian Bioinformatics Workshops ( and a faculty advisor for the Vancouver Bioinformatics Users Group ( Dr. Hsiao completed his PhD at SFU under Dr. Fiona Brinkman's supervision, and a post-doctoral fellowship in Dr. Claire Fraser's laboratory at the Institute for Genome Sciences in University of Maryland School of Medicine. 


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