Rubella case definition

Confirmed Case
Laboratory confirmation of infection in the absence of recent (i.e., in the previous 28 days) immunization with rubella-containing vaccine:  

• Isolation of rubella virus from an appropriate clinical specimen OR
• Detection of rubella virus RNA OR
• Significant (e.g. fourfold or greater) rise in serum rubella IgG antibody titre between acute and convalescent sera OR
• Detection of rubella IgM antibody using a recommended assay in a person with en epidemiologic link to a laboratory-confirmed case or who had recently travelled to an area of known rubella activity OR
• Clinical illness¹ in a person who is epidemiologically linked to a laboratory confirmed case  

Clinical / Probable Case

Clinical illness¹

• In the absence of appropriate laboratory tests,       
• In the absence of an epidemiologic link to a laboratory-confirmed case    
• In a person who has recently travelled to an area of known rubella activity  

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